Hydroxytamoxifen是什么
WebTamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast … http://www.bjbalb.com/html/Other-Cell-Biological-Reagent/M00283.html
Hydroxytamoxifen是什么
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Web4-hydroxytamoxifen 是他莫昔芬和选择性雌激素受体拮抗剂的主要代谢产物。它增强了雌二醇对MA诱导的黑质纹状体DA耗竭的保护作用。 [1] 4-Hydroxytamoxifen具有超氧阴离 … Web13 jun. 2005 · Afimoxifene (4-Hydroxytamoxifen, trade name TamoGel) is a new estrogen inhibitor under investigation for a variety of estrogen-dependent conditions, including cyclic breast pain and gynecomastia. TamoGel is formulated using Enhanced Hydroalcoholic Gel (EHG) Technology. This technology enables percutaneous delivery of drugs that cannot …
Web百度百科是一部内容开放、自由的网络百科全书,旨在创造一个涵盖所有领域知识,服务所有互联网用户的中文知识性百科全书。在这里你可以参与词条编辑,分享贡献你的知识。 Web这是首个获得美国FDA批准用于高危女性乳腺癌预防的药物,可降低乳腺癌风险多达40%;在目前所有获批4款乳腺癌预防药物中,他莫昔芬也是 唯一被美国FDA批准同时用于绝经 …
Web29 aug. 2024 · 人乳腺癌MCF-7他莫昔芬耐药细胞株的建立及鉴定 莫志强,涂刚,杨光伦 (400016 重庆医科大学附属第一医院) [摘要] 目的 构建人乳腺癌细胞MCF-7他莫昔芬(Tamoxifen,TAM)耐药细胞模型,并鉴定其耐药性。. 方法 采用高浓度短时间4-羟他莫昔芬 (4-hydroxytamoxifen,OHT ... http://www.ichacha.net/hydroxytamoxifen-induced.html
WebTamoxifen 是一种有效的 Hsp90 激活剂,可增强 Hsp90 分子伴侣 ATPase 的活性。 Tamoxifen 还可以有效抑制传染性 EBOV Zaire 和 Marburg (MARV) , IC50 分别为 0.1 …
Web氟伏沙明(Fluvoxamine)是一种选择性5-羟色胺再吸收抑制剂(SSRI)型的抗抑郁药,其药物形态为马来酸氟伏沙明(Fluvoxamine Maleate),商品名为“兰释”(Luvox)。 在临 … high fob dietWeb4-Hydroxytamoxifen (4-OHT) is a metabolite of the antiestrogen, tamoxifen, in humans and other mammals. Both the Z (trans) and E (cis) 4-OHT isomers are antiestrogens in the … how i can buy stocksWeb1 jan. 1999 · HPLC separation (methanol–ammonium acetate eluent) with electrospray SIM detection of α-hydroxytamoxifen ([M + H] +, m/z 388) and the internal standard, toremifene (m/z 406).(A) Authentic standards of (I) α-hydroxytamoxifen (25 μM) and (II) toremifene (50 μM).(B) α-Hydroxytamoxifen and endogenous isobaric material from (I) rat liver … how i cancel my facebook accountWeb4-Hydroxytamoxifen (Monohydroxytamoxifen) is a selective ostrogen receptor antagonist, with an IC 50 of 3.3 nM for the [ 3 H]oestradiol binding to oestrogen receptor. 4 … how i can clean my laptopWebEndoxifen wordt gezien als de belangrijkste metaboliet, mede omdat de steady-state serumconcentratie van endoxifen ongeveer vijfmaal hoger is dan de concentratie van 4-hydroxytamoxifen. De behandeling met tamoxifen – waarbij nu iedereen in principe 20 mg krijgt – kan mogelijk optimaler door individueel te doseren op basis van de concentraties … high fobWeb27 aug. 2024 · 4-Hydroxytamoxifen(单羟基三苯氧胺)是一种选择性雌激素受体拮抗剂, [3 H]雌二醇与雌激素受体结合的IC 50为3.3 nM 。 4-Hydroxytamoxifen(10,100 nM)能 … how i can change wi fi speed up to 2 mbpsWeb用(Z)-4-hydroxytamoxifen对已接受0 ~ 2 μg雌二醇皮下注射的未成熟大鼠灌胃。 与给予雌二醇的对照组比,这两种化合物与子宫湿重的减少呈剂量相关性。 以每天1 μg的剂 … high foam platform sandals