Phenol genotoxicity
WebMay 6, 2010 · • Maximal daily intake of a genotoxic impurity at which negligible increased risk for cancer exists • Generic limit based on database of several hundred genotoxic … WebIn the pharmacokinetic study, PNP was well absorbed dermally, validating the negative dermal carcinogenicity assessment. These results indicate that PNP should be …
Phenol genotoxicity
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WebMay 1, 1990 · They observed that phenol is not toxic, hydroquinone is weakly toxic, but the mixture induces a dramatic and significant decrease in bone marrow cellularity. In the … WebPhenol but not the other monitored metabolites was also positively correlated with MN frequency (P less than 0.03). Thus, our data show that the formation of genotoxic metabolites from BZ probably involves hydroxyl radicals and ttM as well as phenol are likely to be responsible for the clastogenic effect of benzene in vivo. Publication types
WebIntegrated Risk Information System US EPA WebThe primary purpose of this chapter is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective on the toxicology of pentachloro-phenol. It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on …
WebPhenol can affect you when inhaled and may be absorbed through the skin. Because this is a MUTAGEN, handle it as a possible carcinogen--WITH EXTREME CAUTION. Contact can … WebPhenol is considered to be an in-vivo somatic mutagen. It is assumed that there is a threshold for genotoxicity for oral exposure due to first-pass metabolism and …
WebIt has been hypothesized that the genotoxicity of phenol on bone marrow results from the following chain of events: phenol is conjugated in the …
WebPhenol is a colorless or white solid when it is pure; however, it is usually sold and used as a liquid. (1) The odor threshold for phenol is 0.04 parts per million (ppm), with a strong very … paw patrol streaming platformWebGenotoxicity Reproductive toxicity References 1. EVALUATION 1.1 Introduction The Committee evaluated a group of 29 aliphatic and aromatic flavouring agents (see Table 1) that included eucalyptol (No. 1234) and anisole (No. 1241) by the Procedure for the Safety Evaluation of Flavouring Agents (see Figure 1, Introduction). paw patrol store ownerWebPhenol and cresols are common toxic environmental pollutants. In this study, the micronucleus assay and the alkaline single cell gel electrophoresis (SCGE) technique have … screenshot of iphone seWebresearch article on phenol genotoxicity was retrieved, while no new publications on general toxicity were found. Concerning genotoxicity, phenol showed DNA-damaging activity in tests in vitro in yeast and mammalian cells. In studies in vivo with oral administration, … paw patrol streaming freeWebJul 1, 2005 · Phenol and cresols are common toxic environmental pollutants. In this study, the micronucleus assay and the alkaline single cell gel electrophoresis (SCGE) technique … paw patrol strap watchWebGenotoxicity associated with haem, N-nitroso compounds, and heterocyclic amines has been proposed as a mechanism underpinning this association. Citation 7 Amongst … paw patrol story timeWebAllium cepa (A. cepa) has been recognized as a promising genetic model to detect the toxicity of industrial wastewater, contaminated soil, river water, nuclear contamination and even for those systems which are considered non toxic. A. cepa is distinguished as a low cost test, easy to handle and sensitive to both in vivo and in vitro models. paw patrol stream online