Polypyrimidine tract-binding protein
WebMay 12, 2006 · The machinery for hepatitis C virus (HCV) RNA replication is still poorly characterized. The relationship between HCV RNA replication and translation is also not … WebPolypyrimidine Tract-Binding Protein 29%. Neoplasms 29%. RNA Recognition Motif 27%. Tissue Array Analysis 26%. Neoplasm Metastasis 22%. 5' Untranslated Regions 21%. RNA …
Polypyrimidine tract-binding protein
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WebAug 23, 2024 · Metabolic and proliferative state of vascular adventitial fibroblasts in pulmonary hypertension is regulated through a MicroRNA-124/PTBP1 (polypyrimidine tract binding protein 1)/pyruvate kinase muscle axis. Circulation. 2024; 136:2468–2485. doi: 10.1161/CIRCULATIONAHA.117.028069 Link Google Scholar; 8. WebFig. 5. The effects of glucose, IBMX and DETAnonoate on insulin mRNA levels (A) and insulin (B) and total protein (C) biosynthesis in INS-1 cells. (A) INS-1 cells were cultured …
WebInhibiting DNA synthesis and proliferation of CRC cells by targeting the inhibitor of apoptosis-stimulating protein of p53, 13 reducing the levels of pentose phosphate … WebDec 27, 2024 · Polypyrimidine tract–binding protein 1 (PTBP1), an essential gene for the Warburg effect, regulates this cancer‐specific energy metabolism via alternative splicing (AS) of pyruvate kinase. 6 PTBP1 decreases the expression of the M1 isoform of pyruvate kinase (PKM1) and promotes the expression of PKM2, which leads mainly to a metabolic …
WebThe polypyrimidine tract binding (PTB) protein family of RBPs are important posttranscriptional regulators of gene expression. In the nervous system, the function and importance of PTB protein 2 ... WebJul 1, 2012 · A protein of molecular size 62,000 daltons (p62) was detected in HeLa cell nuclear extracts by UV cross-linking to mRNA precursors. p62 binds specifically to the polypyrimidine tract of the 3 ...
WebJun 15, 2024 · Polypyrimidine tract-binding protein 1(PTB) IRES CVB3, PV (5, 8) F8VXH9 Poly(rC)-binding protein 2 CL, IRES PV, CVB3 (6, 15) E7EQG2 Eukaryotic initiation factor …
WebFeb 22, 2004 · Tillmar, L. & Welsh, N. Hypoxia may increase rat insulin mRNA levels by promoting binding of the polypyrimidine tract-binding protein (PTB) to the pyrimidine-rich … earth 2 new 52 supermanPolypyrimidine tract-binding protein, also known as PTB or hnRNP I, is an RNA-binding protein. PTB functions mainly as a splicing regulator, although it is also involved in alternative 3' end processing, mRNA stability and RNA localization. Two 2024 studies have shown that depleting PTB mRNA in astrocytes … See more • Polypyrimidine tract See more • polypyrimidine+tract-binding+protein at the US National Library of Medicine Medical Subject Headings (MeSH) See more earth 2 o water eugene oregonWeb] indicated a distinct binding preference of the polypyrimidine tract binding protein for the sequence UCUUC which would be abolished due to the deletion of TTCT in our hemophilia … ctc in schoolWebFurthermore, 3C cleaved the polypyrimidine tract-binding protein (PTB) whose interaction with the HAV IRES had been demonstrated previously. The combined results suggest that … ctc in shippingWebHuR and polypyrimidine tract binding protein (PTB) have been described as 'global regulators' of RNA alternative splicing, stability, and translation in non-neuronal (including … ctc inspectionWebIn addition, polypyrimidine tract-binding protein 1 (PTBP1) is essential for the pro-duction of PKM2 in cancer cells. Recently, several studies focusing on non-coding RNA elucidated PTBP1 or PKM2 regulatory mechanisms, including control … ctc intensive family supportWebThe U1 snRNP binds to the GU sequence at the 5' splice site of an intron; Splicing factor 1 binds to the intron branch point sequence; U2AF1 binds at the 3' splice site of the intron; U2AF2 binds to the polypyrimidine tract; … earth 2 o water company